Standard

Migraine

near ITPK1 · rs28540738

Where this position leads

Condition: Migraine

rs28540738 Condition: Migraine Migraine Condition rs28540738 rs28540738 near ITPK1

What the study found

Who was studied 85,726 European ancestry cases, 803,292 European ancestry controls.

The effect The reported allele is G; the catalogue records no effect size ; p = 4 × 10−12.

How common The G allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 14, band 14q32.12 — between genes, 8.9 kb from ITPK1.

What each result means

A/A No copy of the version the research linked to Migraine. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Migraine. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Migraine. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs28540738

What is rs28540738?

rs28540738 is a single position in the genome, in or near the near ITPK1 gene. Published research associates it with migraine. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs28540738 linked to?

On MyGeneLog this position is linked to Migraine. The research behind each link, and its sources, are set out on that condition page.

Does having rs28540738 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28540738 come from?

GWAS Catalog, Communications biology 2021, PMID:34294844. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Migraine (rs28540738). MyGeneLog™. https://www.mygenelog.com/variants/rs28540738

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