Sensitive

Gastric cancer

near RPL3P2 · rs2853940

Where this position leads

Condition: Non-Cardia Gastric Cancer

rs2853940 Condition: Non-Cardia Gastric Cancer Non-Cardia Gastric Cancer Condition rs2853940 rs2853940 near RPL3P2

What the study found

Who was studied 1,029 European ancestry cases, 475,087 European ancestry controls, 7,921 East Asian ancestry cases, 159,201 East Asian ancestry controls.

The effect Each copy of the C allele shifted the measure 0.109 higher (95% confidence interval 0.078-0.14); p = 8 × 10−12.

Where it sits Chromosome 6, band 6p21.33 — between genes, 0.4 kb from RPL3P2.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Gastric cancer compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Gastric cancer.
T/T Published research associates this genotype with typical/baseline likelihood of Gastric cancer — no copies of the reported risk allele.
Source

Questions about rs2853940

What is rs2853940?

rs2853940 is a single position in the genome, in or near the near RPL3P2 gene. Published research associates it with gastric cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2853940 linked to?

On MyGeneLog this position is linked to Non-Cardia Gastric Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs2853940 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2853940 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Gastric cancer (rs2853940). MyGeneLog™. https://www.mygenelog.com/variants/rs2853940

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