CAV2 · rs28503222
Where this position leads
Condition: Intraocular Pressure
What the study found
Who was studied 31,269 European ancestry individuals.
The effect Each copy of the C allele shifted the measure 0.211 mmHg higher (95% confidence interval 0.14-0.28); p = 1 × 10−9.
How common The C allele had a frequency of about 18% in the people studied.
Where it sits Chromosome 7, band 7q31.2 — in an intron of CAV2.
rs28503222 is a single position in the genome, in or near the CAV2 gene. Published research associates it with intraocular pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Intraocular Pressure. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Communications biology 2019, PMID:31798171. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Intraocular pressure (rs28503222). MyGeneLog™. https://www.mygenelog.com/variants/rs28503222