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Epilepsy

PCDH7 · rs28498976

Where this position leads

Condition: Epilepsy

rs28498976 Condition: Epilepsy Epilepsy Condition rs28498976 rs28498976 PCDH7

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Epilepsy compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Epilepsy.
G/G Published research associates this genotype with typical/baseline likelihood of Epilepsy — no copies of the reported risk allele.
Source
Genetic determinants of common epilepsies: a meta-analysis of genome-wide association studies
International League Against Epilepsy Consortium on Complex Epilepsies. Electronic address: epilepsy-austin@unimelb.edu.au
The Lancet. Neurology · 2014 · PMID 25087078

Questions about rs28498976

What is rs28498976?

rs28498976 is a single position in the genome, in or near the PCDH7 gene. Published research associates it with epilepsy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs28498976 linked to?

On MyGeneLog this position is linked to Epilepsy. The research behind each link, and its sources, are set out on that condition page.

Does having rs28498976 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28498976 come from?

GWAS Catalog, Lancet Neurol 2014, PMID:25087078. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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