Standard
Serum dimethylarginine levels (asymmetric/symetric ratio)
DDAH1 · rs28489187
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Serum dimethylarginine levels (asymmetric/symetric ratio) — no copies of the reported risk allele.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Serum dimethylarginine levels (asymmetric/symetric ratio).
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Serum dimethylarginine levels (asymmetric/symetric ratio) compared to the general population.
Source
Genome-wide association study on dimethylarginines reveals novel AGXT2 variants associated with heart rate variability but not with overall mortality
Seppälä I,
Kleber ME,
Lyytikäinen LP,
Hernesniemi JA,
Mäkelä KM,
Oksala N,
Laaksonen R,
Pilz S,
Tomaschitz A,
Silbernagel G,
Boehm BO,
Grammer TB
and 10 more — show all
European heart journal · 2014 · PMID 24159190
Questions about rs28489187
What is rs28489187?
rs28489187 is a single position in the genome, in or near the DDAH1 gene. Published research associates it with serum dimethylarginine levels (asymmetric/symetric ratio). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs28489187 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs28489187 come from?
GWAS Catalog, Eur Heart J 2013, PMID:24159190. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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