0 5122Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total5Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 241,168 British ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0188 kg lower (95% confidence interval 0.014-0.024); p = 3 × 10−13.
Where it sits Chromosome 8, band 8p23.1 — in an intron of MCPH1.
What each result means
A/ANo copy of the version the research linked to Birth weight (winsorised). This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Birth weight (winsorised). That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Birth weight (winsorised). That is the strongest link of the three results. A link in a study is not a diagnosis.
rs28477757 is a single position in the genome, in or near the MCPH1 gene. Published research associates it with birth weight (winsorised). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs28477757 linked to?
On MyGeneLog this position is linked to Birth Weight. The research behind each link, and its sources, are set out on that condition page.
Does having rs28477757 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs28477757 come from?
GWAS Catalog, Diabetologia 2025, PMID:40210729. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 5122Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total5Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.