0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 12,525 European ancestry cases, 668,014 European ancestry controls, 1,219 East Asian ancestry cases, 132,032 East Asian ancestry controls.
The effect
The reported allele is C; the catalogue records no effect size
; p = 5 × 10−10.
Where it sits Chromosome 6, band 6p22.3 — between genes, 53.2 kb from SPTLC1P2.
What each result means
C/CTwo copies of the version the research linked to Type 1 diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/GOne copy of the version the research linked to Type 1 diabetes. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Type 1 diabetes. This is the starting point the study compared everyone against.
Diabetic medicine : a journal of the British Diabetic Association · 2026 · PMID 42594184
Questions about rs28464459
What is rs28464459?
rs28464459 is a single position in the genome, in or near the near SPTLC1P2 gene. Published research associates it with type 1 diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs28464459 linked to?
On MyGeneLog this position is linked to Type 1 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Does having rs28464459 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs28464459 come from?
GWAS Catalog, Diabetic medicine : a journal of the British Diabetic Association 2026, PMID:42594184. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Type 1 diabetes (rs28464459). MyGeneLog™. https://www.mygenelog.com/variants/rs28464459