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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 112,866 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.036 lower (95% confidence interval 0.024-0.048); p = 6 × 10−9.
How common The T allele had a frequency of about 12% in the people studied.
Where it sits Chromosome 9, band 9q34.3 — in an intron of EXD3.
What each result means
C/CNo copy of the version the research linked to Ease of getting up in the morning. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Ease of getting up in the morning. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Ease of getting up in the morning. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2017 · PMID 28604731 · open access
Questions about rs28458909
What is rs28458909?
rs28458909 is a single position in the genome, in or near the EXD3 gene. Published research associates it with ease of getting up in the morning. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs28458909 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs28458909 come from?
GWAS Catalog, Nat Genet 2017, PMID:28604731. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Ease of getting up in the morning (rs28458909). MyGeneLog™. https://www.mygenelog.com/variants/rs28458909