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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 288,127 East Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0351 lower (95% confidence interval 0.029-0.041); p = 3 × 10−31.
How common The A allele had a frequency of about 30% in the people studied.
Where it sits Chromosome 4, band 4q22.1 — between genes, 0.4 kb from HSD17B13.
What each result means
A/ATwo copies of the version the research linked to Aspartate aminotransferase levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Aspartate aminotransferase levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Aspartate aminotransferase levels. This is the starting point the study compared everyone against.
Nature communications · 2022 · PMID 36333282 · open access
Questions about rs28456144
What is rs28456144?
rs28456144 is a single position in the genome, in or near the near HSD17B13 gene. Published research associates it with aspartate aminotransferase levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs28456144 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs28456144 come from?
GWAS Catalog, Nature communications 2022, PMID:36333282. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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