Sensitive

Coronary artery disease

ADAMTS7 · rs28455815

Where this position leads

Condition: Coronary Artery Disease

rs28455815 Condition: Coronary Artery Disease Coronary Artery Disease Condition rs28455815 rs28455815 ADAMTS7

What the study found

Who was studied 15,302 Japanese ancestry cases, 36,140 Japanese ancestry controls.

The effect Each copy of the T allele carried 1.12 times the odds of Coronary artery disease (95% confidence interval 1.08-1.16); p = 1 × 10−8.

How common The T allele had a frequency of about 54% in the people studied.

Where it sits Chromosome 15, band 15q25.1 — inside MORF4L1.

What each result means

C/C No copy of the version the research linked to Coronary artery disease. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Coronary artery disease. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Coronary artery disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs28455815

What is rs28455815?

rs28455815 is a single position in the genome, in or near the ADAMTS7 gene. Published research associates it with coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs28455815 linked to?

On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs28455815 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28455815 come from?

GWAS Catalog, Circulation. Genomic and precision medicine 2020, PMID:32469254. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Coronary artery disease (rs28455815). MyGeneLog™. https://www.mygenelog.com/variants/rs28455815

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