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Trans fatty acid levels

FADS2 · rs2845573

What the study found

Who was studied 8,013 European ancestry individuals; replicated in 1,082 African American individuals, 669 Chinese ancestry individuals, 657 Hispanic individuals.

The effect Each copy of the A allele shifted the measure 0.0044 lower (95% confidence interval 0.0028-0.006); p = 1 × 10−8.

How common The A allele had a frequency of about 92% in the people studied.

Where it sits Chromosome 11, band 11q12.2 — in an intron of FADS2.

What each result means

A/A Two copies of the version the research linked to Trans fatty acid levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Trans fatty acid levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Trans fatty acid levels. This is the starting point the study compared everyone against.
Source

Questions about rs2845573

What is rs2845573?

rs2845573 is a single position in the genome, in or near the FADS2 gene. Published research associates it with trans fatty acid levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2845573 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2845573 come from?

GWAS Catalog, The American journal of clinical nutrition 2015, PMID:25646338. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Trans fatty acid levels (rs2845573). MyGeneLog™. https://www.mygenelog.com/variants/rs2845573

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