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Who was studied 41,917 European ancestry bipolar disorder cases, 12,366 European ancestry ulcerative colitis cases, 405,158 European ancestry controls.
The effect
Each copy of the C allele shifted the measure 0.014 higher (95% confidence interval 0.01-0.018); p = 2 × 10−10.
Where it sits Chromosome 6, band 6p21.33 — between genes, 2.1 kb from NAPGP2.
What each result means
C/CTwo copies of the version the research linked to Bipolar disorder or ulcerative colitis (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Bipolar disorder or ulcerative colitis (MTAG). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Bipolar disorder or ulcerative colitis (MTAG). This is the starting point the study compared everyone against.
Journal of affective disorders · 2024 · PMID 38154582
Questions about rs2844697
What is rs2844697?
rs2844697 is a single position in the genome, in or near the near NAPGP2 gene. Published research associates it with bipolar disorder or ulcerative colitis (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2844697 linked to?
On MyGeneLog this position is linked to Ulcerative Colitis. The research behind each link, and its sources, are set out on that condition page.
Does having rs2844697 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2844697 come from?
GWAS Catalog, Journal of affective disorders 2024, PMID:38154582. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Bipolar disorder or ulcerative colitis (MTAG) (rs2844697). MyGeneLog™. https://www.mygenelog.com/variants/rs2844697