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QT dynamics during exercise

near SLC35F1 · rs28436726

What the study found

Who was studied 28,449 European ancestry women, 24,412 European ancestry men.

The effect Each copy of the G allele shifted the measure 0.107 bpm higher (95% confidence interval 0.085-0.129); p = 4 × 10−22.

How common The G allele had a frequency of about 94% in the people studied.

Where it sits Chromosome 6, band 6q22.31 — between genes, 26 kb from SLC35F1.

What each result means

A/A No copy of the version the research linked to QT dynamics during exercise. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to QT dynamics during exercise. That is a smaller link than two copies.
G/G Two copies of the version the research linked to QT dynamics during exercise. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs28436726

What is rs28436726?

rs28436726 is a single position in the genome, in or near the near SLC35F1 gene. Published research associates it with qt dynamics during exercise. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs28436726 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28436726 come from?

GWAS Catalog, Circulation. Genomic and precision medicine 2020, PMID:32527199. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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QT dynamics during exercise (rs28436726). MyGeneLog™. https://www.mygenelog.com/variants/rs28436726

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