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Edge-level brain connectivity (multivariate analysis)

DCLK2 · rs28413051

What the study found

Who was studied 30,810 British ancestry individuals.

The effect Each copy of the G allele shifted the measure 6.28 z score higher; p = 3 × 10−10.

How common The G allele had a frequency of about 78% in the people studied.

Where it sits Chromosome 4, band 4q31.23 — in an intron of DCLK2.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Edge-level brain connectivity (multivariate analysis) — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Edge-level brain connectivity (multivariate analysis).
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Edge-level brain connectivity (multivariate analysis) compared to the general population.
Source

Questions about rs28413051

What is rs28413051?

rs28413051 is a single position in the genome, in or near the DCLK2 gene. Published research associates it with edge-level brain connectivity (multivariate analysis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs28413051 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28413051 come from?

GWAS Catalog, Science advances 2023, PMID:36800424. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Edge-level brain connectivity (multivariate analysis) (rs28413051). MyGeneLog™. https://www.mygenelog.com/variants/rs28413051

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