0 624Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others4Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 14,361 European ancestry cases, 43,923 European ancestry controls, 8,267 East Asian ancestry cases, 244,741 East Asian ancestry controls.
The effect
Each copy of the A allele carried 0.85 times the odds of Rheumatoid arthritis (95% confidence interval 0.82-0.88); p = 2 × 10−19.
Where it sits Chromosome 14, band 14q32.33 — between genes, 2.9 kb from PLD4.
What each result means
A/ATwo copies of the version the research linked to Rheumatoid arthritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Rheumatoid arthritis. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Rheumatoid arthritis. This is the starting point the study compared everyone against.
Annals of the rheumatic diseases · 2021 · PMID 33310728 · open access
Questions about rs2841275
What is rs2841275?
rs2841275 is a single position in the genome, in or near the near PLD4 gene. Published research associates it with rheumatoid arthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2841275 linked to?
On MyGeneLog this position is linked to Rheumatoid Arthritis. The research behind each link, and its sources, are set out on that condition page.
Does having rs2841275 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2841275 come from?
GWAS Catalog, Annals of the rheumatic diseases 2021, PMID:33310728. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 624Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others4Total6Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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