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Who was studied 768 Hispanic or Latin American cases, 58,733 Hispanic or Latin American controls, 31,142 European ancestry cases, 404,406 European ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.167 higher (95% confidence interval 0.14-0.2); p = 4 × 10−35.
How common The T allele had a frequency of about 85% in the people studied.
Where it sits Chromosome 8, band 8q22.2 — in an intron of RGS22.
What each result means
A/ANo copy of the version the research linked to Basal cell carcinoma (PheCode 172.21). This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Basal cell carcinoma (PheCode 172.21). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Basal cell carcinoma (PheCode 172.21). That is the strongest link of the three results. A link in a study is not a diagnosis.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs28410444
What is rs28410444?
rs28410444 is a single position in the genome, in or near the RGS22 gene. Published research associates it with basal cell carcinoma (phecode 172.21). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs28410444 linked to?
On MyGeneLog this position is linked to Basal Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs28410444 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs28410444 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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