Platelet reactivity in response to clopidogrel treatment
NPM1P26 · rs28399513
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,592 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.448 lower (95% confidence interval 0.38-0.52); p = 1 × 10−33.
How common The T allele had a frequency of about 83% in the people studied.
Where it sits Chromosome 10, band 10q23.33 — in an intron of CYP2C19.
What each result means
A/ANo copy of the version the research linked to Platelet reactivity in response to clopidogrel treatment. This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Platelet reactivity in response to clopidogrel treatment. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Platelet reactivity in response to clopidogrel treatment. That is the strongest link of the three results. A link in a study is not a diagnosis.
Clinical pharmacology and therapeutics · 2020 · PMID 32472697
Questions about rs28399513
What is rs28399513?
rs28399513 is a single position in the genome, in or near the NPM1P26 gene. Published research associates it with platelet reactivity in response to clopidogrel treatment. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs28399513 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs28399513 come from?
GWAS Catalog, Clinical pharmacology and therapeutics 2020, PMID:32472697. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Platelet reactivity in response to clopidogrel treatment (rs28399513). MyGeneLog™. https://www.mygenelog.com/variants/rs28399513