APBA2 · rs28398028
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 171,614 European ancestry cases, 283,550 European ancestry controls.
The effect Each copy of the T allele shifted the measure 0.55 higher (95% confidence interval 0.4-0.7); p = 1 × 10−12.
How common The T allele had a frequency of about 0% in the people studied.
Where it sits Chromosome 15, band 15q13.1 — in an intron of APBA2.
rs28398028 is a single position in the genome, in or near the APBA2 gene. Published research associates it with hair colour (natural, before greying): dark brown (ukb data field 1747_4). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nature genetics 2021, PMID:34737426. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Hair colour (natural, before greying): Dark brown (UKB data field 1747_4) (rs28398028). MyGeneLog™. https://www.mygenelog.com/variants/rs28398028