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Who was studied 98,316 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.00124 higher (95% confidence interval 0.0011-0.0014); p = 3 × 10−38.
How common The C allele had a frequency of about 46% in the people studied.
Where it sits Chromosome 4, band 4q21.1 — in an intron of SHROOM3.
What each result means
C/CTwo copies of the version the research linked to Creatinine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Creatinine levels. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Creatinine levels. This is the starting point the study compared everyone against.
Ophthalmology science · 2024 · PMID 39091897 · open access
Questions about rs28394165
What is rs28394165?
rs28394165 is a single position in the genome, in or near the SHROOM3 gene. Published research associates it with creatinine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs28394165 linked to?
On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.
Does having rs28394165 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs28394165 come from?
GWAS Catalog, Ophthalmology science 2024, PMID:39091897. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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