0 142129Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple1China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others9Total14Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 10,094 European ancestry current and former smoker individuals, 3,260 African American current and former smoker individuals, 178 current and former smoker individuals.
The effect
Each copy of the A allele shifted the measure 0.019 lower; p = 5 × 10−10.
How common The A allele had a frequency of about 89% in the people studied.
Where it sits Chromosome 11, band 11q22.2 — inside MMP12.
What each result means
A/ATwo copies of the version the research linked to Post bronchodilator FEV1/FVC ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Post bronchodilator FEV1/FVC ratio. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Post bronchodilator FEV1/FVC ratio. This is the starting point the study compared everyone against.
rs28381684 is a single position in the genome, in or near the MMP12 gene. Published research associates it with post bronchodilator fev1/fvc ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs28381684 linked to?
On MyGeneLog this position is linked to Pulmonary Function (Lung Capacity). The research behind each link, and its sources, are set out on that condition page.
Does having rs28381684 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs28381684 come from?
GWAS Catalog, BMC genetics 2015, PMID:26634245. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 142129Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple1China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others9Total14Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Post bronchodilator FEV1/FVC ratio (rs28381684). MyGeneLog™. https://www.mygenelog.com/variants/rs28381684