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Who was studied 26,279 European ancestry cases, 442,230 European ancestry controls, 2,590 South Asian ancestry cases, 1,720 South Asian ancestry controls.
The effect
Each copy of the T allele shifted the measure 0.126 lower (95% confidence interval 0.069-0.183); p = 1 × 10−13.
Where it sits Chromosome 6, band 6p22.1 — between genes, 24.6 kb from NOP56P1.
What each result means
G/GNo copy of the version the research linked to Psoriasis. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Psoriasis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Psoriasis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Journal of translational medicine · 2025 · PMID 39885523 · open access
Questions about rs28381664
What is rs28381664?
rs28381664 is a single position in the genome, in or near the near NOP56P1 gene. Published research associates it with psoriasis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs28381664 linked to?
On MyGeneLog this position is linked to Psoriasis. The research behind each link, and its sources, are set out on that condition page.
Does having rs28381664 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs28381664 come from?
GWAS Catalog, Journal of translational medicine 2025, PMID:39885523. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 5122Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total5Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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