3 28224123212Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity2Meta AI4Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others12Total28Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 1,972 East Asian ancestry cases, 12,236 East Asian ancestry controls.
The effect
Each copy of the T allele carried 1.85 times the odds of IgG4-related disease (95% confidence interval 1.699-2.026); p = 3 × 10−44.
Where it sits Chromosome 6, band 6p21.32 — between genes, 16.9 kb from HLA-DQB1.
What each result means
C/CNo copy of the version the research linked to IgG4-related disease. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to IgG4-related disease. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to IgG4-related disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Annals of the rheumatic diseases · 2026 · PMID 41298177
Questions about rs28371251
What is rs28371251?
rs28371251 is a single position in the genome, in or near the near HLA-DQB1 gene. Published research associates it with igg4-related disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs28371251 linked to?
On MyGeneLog this position is linked to IgG4-Related Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs28371251 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs28371251 come from?
GWAS Catalog, Annals of the rheumatic diseases 2026, PMID:41298177. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
3 28224123212Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity2Meta AI4Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others12Total28Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.