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Influenza

B3GALT5 · rs2837112

What the study found

Who was studied 1,240 African ancestry cases, 22,582 African ancestry controls, 2,480 Hispanic or Latin American cases, 34,308 Hispanic or Latin American controls, 36,474 European ancestry cases, 1,339,760 European ancestry controls, 162 South Asian ancestry cases, 10,914 South Asian ancestry controls.

The effect Each copy of the A allele carried 0.92 times the odds of Influenza (95% confidence interval 0.906-0.934); p = 4 × 10−28.

How common The A allele had a frequency of about 47% in the people studied.

Where it sits Chromosome 21, band 21q22.2 — in the 3′ untranslated region of B3GALT5.

What each result means

A/A Two copies of the version the research linked to Influenza. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Influenza. That is a smaller link than two copies.
G/G No copy of the version the research linked to Influenza. This is the starting point the study compared everyone against.
Source

Questions about rs2837112

What is rs2837112?

rs2837112 is a single position in the genome, in or near the B3GALT5 gene. Published research associates it with influenza. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2837112 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2837112 come from?

GWAS Catalog, Nature genetics 2024, PMID:39103650. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Influenza (rs2837112). MyGeneLog™. https://www.mygenelog.com/variants/rs2837112

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