Standard

Body mass index

LOC400867 · rs2836768

Where this position leads

Condition: Childhood Body Mass Index

rs2836768 Condition: Childhood Body Mass Index Childhood Body Mass Index Condition rs2836768 rs2836768 LOC400867

What the study found

Who was studied up to 72,390 Japanese ancestry women, up to 85,894 Japanese ancestry men; replicated in up to 10,048 Japanese ancestry women, up to 5,098 Japanese ancestry men, up to 181,999 European ancestry women, up to 140,155 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.02 lower (95% confidence interval 0.014-0.026); p = 6 × 10−12.

How common The T allele had a frequency of about 41% in the people studied.

Where it sits Chromosome 21, band 21q22.2 — in an intron of ETS2-AS1.

What each result means

G/G No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2836768

What is rs2836768?

rs2836768 is a single position in the genome, in or near the LOC400867 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2836768 linked to?

On MyGeneLog this position is linked to Childhood Body Mass Index. The research behind each link, and its sources, are set out on that condition page.

Does having rs2836768 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2836768 come from?

GWAS Catalog, Nature genetics 2017, PMID:28892062. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Body mass index (rs2836768). MyGeneLog™. https://www.mygenelog.com/variants/rs2836768

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