Standard

Body mass index

near ETS2 · rs2836754

Where this position leads

Condition: Obesity and Body Weight

rs2836754 Condition: Obesity and Body Weight Obesity and Body Weight Condition rs2836754 rs2836754 near ETS2

What the study found

Who was studied 315,347 European ancestry individuals, 8,322 Hispanic/Latino individuals, 7,290 East Asian ancestry individuals, 3,069 African American individuals, 459 South Asian ancestry individuals; replicated in 431,743 European ancestry individuals, 9,275 South Asian ancestry individuals, 8,261 African British individuals, 1,822 East Asian ancestry individuals, 7,620 individuals.

The effect Each copy of the T allele shifted the measure 0.017 lower; p = 7 × 10−11.

Where it sits Chromosome 21, band 21q22.2 — in an intron of ETS2-AS1.

What each result means

C/C No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2836754

What is rs2836754?

rs2836754 is a single position in the genome, in or near the near ETS2 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2836754 linked to?

On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs2836754 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2836754 come from?

GWAS Catalog, Genetics 2018, PMID:30108127. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs2836754). MyGeneLog™. https://www.mygenelog.com/variants/rs2836754

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