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TG protein levels

near ATP5MGP4 · rs28367132

Where this position leads

Condition: Celiac Disease

rs28367132 Condition: Celiac Disease Celiac Disease Condition rs28367132 rs28367132 near ATP5MGP4

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.055 lower (95% confidence interval 0.041-0.069); p = 5 × 10−16.

How common The A allele had a frequency of about 20% in the people studied.

Where it sits Chromosome 4, band 4q31.23 — between genes, 14.9 kb from ATP5MGP4.

What each result means

A/A Two copies of the version the research linked to TG protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to TG protein levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to TG protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs28367132

What is rs28367132?

rs28367132 is a single position in the genome, in or near the near ATP5MGP4 gene. Published research associates it with tg protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs28367132 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs28367132 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28367132 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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TG protein levels (rs28367132). MyGeneLog™. https://www.mygenelog.com/variants/rs28367132

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