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Total fatty acid levels

near HLA-DRB1 · rs28366337

What the study found

Who was studied 239,268 European ancestry individuals.

The effect The reported allele is G; the catalogue records no effect size ; p = 1 × 10−12.

Where it sits Chromosome 6, band 6p21.32 — between genes, 7.1 kb from HLA-DRB1.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Total fatty acid levels — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Total fatty acid levels.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Total fatty acid levels compared to the general population.
Source

Questions about rs28366337

What is rs28366337?

rs28366337 is a single position in the genome, in or near the near HLA-DRB1 gene. Published research associates it with total fatty acid levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs28366337 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28366337 come from?

GWAS Catalog, HGG advances 2025, PMID:40545721. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Total fatty acid levels (rs28366337). MyGeneLog™. https://www.mygenelog.com/variants/rs28366337

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