Serine protease 27 level in Chronic kidney disease with hypertension and no diabetes (15535_3)
FUT3 · rs28362458
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 466 African American individuals.
The effect
Each copy of the T allele shifted the measure 0.78 higher (95% confidence interval 0.66-0.9); p = 1 × 10−12.
How common The T allele had a frequency of about 13% in the people studied.
Where it sits Chromosome 19, band 19p13.3 — a missense change in FUT3.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Serine protease 27 level in Chronic kidney disease with hypertension and no diabetes (15535_3) — no copies of the reported risk allele.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Serine protease 27 level in Chronic kidney disease with hypertension and no diabetes (15535_3).
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Serine protease 27 level in Chronic kidney disease with hypertension and no diabetes (15535_3) compared to the general population.
rs28362458 is a single position in the genome, in or near the FUT3 gene. Published research associates it with serine protease 27 level in chronic kidney disease with hypertension and no diabetes (15535_3). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs28362458 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs28362458 come from?
GWAS Catalog, Kidney international 2022, PMID:35870639. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Serine protease 27 level in Chronic kidney disease with hypertension and no diabetes (15535_3) (rs28362458). MyGeneLog™. https://www.mygenelog.com/variants/rs28362458