Standard

Phosphatidylglycerol(32:1)_[M+OAc]1- levels

near UGT8 · rs28361366

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 5,662 Pakistani ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0762 higher (95% confidence interval 0.055-0.097); p = 1 × 10⁻¹².

Where it sits Chromosome 4, band 4q26 — between genes, 85.6 kb from UGT8.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Phosphatidylglycerol(32:1)_[M+OAc]1- levels compared to the general population.

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Phosphatidylglycerol(32:1)_[M+OAc]1- levels.

T/T Published research associates this genotype with typical/baseline likelihood of Phosphatidylglycerol(32:1)_[M+OAc]1- levels — no copies of the reported risk allele.

Source

Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci

Harshfield EL, Fauman EB, Stacey D, Paul DS, Ziemek D, Ong RMY, Danesh J, Butterworth AS, Rasheed A, Sattar T, Zameer-Ul-Asar, Saleem I

and 18 more — show all

Hina Z, Ishtiaq U, Qamar N, Mallick NH, Yaqub Z, Saghir T, Rizvi SNH, Memon A, Ishaq M, Rasheed SZ, Memon FU, Jalal A, Abbas S, Frossard P, Saleheen D, Wood AM, Griffin JL, Koulman A

BMC medicine · 2021 · PMID 34503513 · open access

Questions about rs28361366

What is rs28361366?

rs28361366 is a single position in the genome, in or near the near UGT8 gene. Published research associates it with phosphatidylglycerol(32:1)_[m+oac]1- levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs28361366 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28361366 come from?

GWAS Catalog, BMC medicine 2021, PMID:34503513. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Phosphatidylglycerol(32:1)_[M+OAc]1- levels (rs28361366). MyGeneLog™. https://www.mygenelog.com/variants/rs28361366

← See all variants