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C-reactive protein levels (UKB data field 30710)

near P2RX4 · rs28360463

Where this position leads

Condition: C-Reactive Protein Levels

rs28360463 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs28360463 rs28360463 near P2RX4

What the study found

Who was studied 394,642 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0298 lower (95% confidence interval 0.024-0.035); p = 3 × 10−26.

How common The A allele had a frequency of about 14% in the people studied.

Where it sits Chromosome 12, band 12q24.31 — between genes, 0.5 kb from P2RX4.

What each result means

A/A Two copies of the version the research linked to C-reactive protein levels (UKB data field 30710). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to C-reactive protein levels (UKB data field 30710). That is a smaller link than two copies.
C/C No copy of the version the research linked to C-reactive protein levels (UKB data field 30710). This is the starting point the study compared everyone against.
Source

Questions about rs28360463

What is rs28360463?

rs28360463 is a single position in the genome, in or near the near P2RX4 gene. Published research associates it with c-reactive protein levels (ukb data field 30710). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs28360463 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs28360463 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28360463 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

C-reactive protein levels (UKB data field 30710) (rs28360463). MyGeneLog™. https://www.mygenelog.com/variants/rs28360463

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