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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 219,768 East Asian ancestry individuals, 677,373 European ancestry individuals, 132,182 individuals.
The effect
Each copy of the A allele shifted the measure 0.024 higher (95% confidence interval 0.018-0.03); p = 7 × 10−15.
Where it sits Chromosome 21, band 21q22.11 — in an intron of LINC00649.
What each result means
A/ATwo copies of the version the research linked to Serum urate levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Serum urate levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Serum urate levels. This is the starting point the study compared everyone against.
Nature communications · 2024 · PMID 38658550 · open access
Questions about rs2834321
What is rs2834321?
rs2834321 is a single position in the genome, in or near the LINC00649 gene. Published research associates it with serum urate levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2834321 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2834321 come from?
GWAS Catalog, Nature communications 2024, PMID:38658550. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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