Sensitive

Inflammatory bowel disease

near CYCSP42 · rs2823286

Where this position leads

Condition: Inflammatory Bowel Disease

rs2823286 Condition: Inflammatory Bowel Disease Inflammatory Bowel Disease Condition rs2823286 rs2823286 near CYCSP42

What the study found

Who was studied 12,924 European ancestry cases, 21,442 European ancestry controls; replicated in 25,683 European ancestry cases, 17,015 European ancestry controls.

The effect Each copy of the G allele carried 1.16 times the odds of Inflammatory bowel disease (95% confidence interval 1.121-1.194); p = 9 × 10−30.

How common The G allele had a frequency of about 71% in the people studied.

Where it sits Chromosome 21, band 21q21.1 — between genes, 44.9 kb from CYCSP42.

What each result means

A/A No copy of the version the research linked to Inflammatory bowel disease. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Inflammatory bowel disease. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Inflammatory bowel disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2823286

What is rs2823286?

rs2823286 is a single position in the genome, in or near the near CYCSP42 gene. Published research associates it with inflammatory bowel disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2823286 linked to?

On MyGeneLog this position is linked to Inflammatory Bowel Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs2823286 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2823286 come from?

GWAS Catalog, Nature 2012, PMID:23128233. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Inflammatory bowel disease (rs2823286). MyGeneLog™. https://www.mygenelog.com/variants/rs2823286

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