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Who was studied 374,756 European ancestry male individuals.
The effect
Each copy of the T allele shifted the measure 0.0259 higher (95% confidence interval 0.022-0.03); p = 3 × 10−40.
How common The T allele had a frequency of about 21% in the people studied.
Where it sits Chromosome 6, band 6p21.31 — in an intron of ILRUN.
What each result means
C/CNo copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
Human molecular genetics · 2019 · PMID 30239722 · open access
Questions about rs2814998
What is rs2814998?
rs2814998 is a single position in the genome, in or near the ILRUN gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2814998 linked to?
On MyGeneLog this position is linked to Obesity and Body Weight, Childhood Body Mass Index. The research behind each link, and its sources, are set out on that condition page.
Does having rs2814998 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2814998 come from?
GWAS Catalog, Human molecular genetics 2019, PMID:30239722. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 121218Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others8Total12Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Body mass index (rs2814998). MyGeneLog™. https://www.mygenelog.com/variants/rs2814998