Standard

Brown vs. black hair color

SLC45A2 · rs28117

Where this position leads

Condition: Hair Color

rs28117 Condition: Hair Color Hair Color Condition rs28117 rs28117 SLC45A2

What the study found

Who was studied 3,750 Iberian ancestry cases, 952 Iberian ancestry controls.

The effect Each copy of the G allele shifted the measure 0.818 lower (95% confidence interval 0.67-0.97); p = 1 × 10−26.

How common The G allele had a frequency of about 11% in the people studied.

Where it sits Chromosome 5, band 5p13.2 — in an intron of SLC45A2.

What each result means

A/A No copy of the version the research linked to Brown vs. black hair color. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Brown vs. black hair color. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Brown vs. black hair color. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs28117

What is rs28117?

rs28117 is a single position in the genome, in or near the SLC45A2 gene. Published research associates it with brown vs. black hair color. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs28117 linked to?

On MyGeneLog this position is linked to Hair Color. The research behind each link, and its sources, are set out on that condition page.

Does having rs28117 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs28117 come from?

GWAS Catalog, Genes 2023, PMID:36672889. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Brown vs. black hair color (rs28117). MyGeneLog™. https://www.mygenelog.com/variants/rs28117

← See all variants