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Basophil forward scatter

near SRGN · rs2805921

What the study found

Who was studied 30,614 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0666 SD units higher (95% confidence interval 0.048-0.085); p = 9 × 10−13.

How common The A allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 10, band 10q22.1 — between genes, 0.3 kb from SRGN.

What each result means

A/A Two copies of the version the research linked to Basophil forward scatter. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Basophil forward scatter. That is a smaller link than two copies.
G/G No copy of the version the research linked to Basophil forward scatter. This is the starting point the study compared everyone against.
Source

Questions about rs2805921

What is rs2805921?

rs2805921 is a single position in the genome, in or near the near SRGN gene. Published research associates it with basophil forward scatter. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2805921 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2805921 come from?

GWAS Catalog, Nature communications 2023, PMID:37596262. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Basophil forward scatter (rs2805921). MyGeneLog™. https://www.mygenelog.com/variants/rs2805921

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