Standard

Coronary dominance (left or co-dominant vs right dominant)

near LINC00841 · rs2802490

What the study found

Who was studied 7,708 European ancestry left or co-dominant individuals, 37,613 European ancestry right dominant individuals, 2,040 Sub-Saharan African ancestry left or co-dominant individuals, 8,280 Sub-Saharan African ancestry right dominant individuals, 738 Hispanic or Latin American left or co-dominant individuals, 3,717 Hispanic or Latin American right dominant individuals, 47 East Asian ancestry left or co-dominant individuals, 287 East Asian ancestry right dominant individuals, 7 South Asian ancestry left or co-dominant individuals, 25 South Asian ancestry right dominant individuals, 98 left or co-dominant individuals, 483 right dominant individuals.

The effect Each copy of the A allele carried 1.14 times the odds of Coronary dominance (left or co-dominant vs right dominant) (95% confidence interval 1.1-1.17); p = 1 × 10−15.

How common The A allele had a frequency of about 55% in the people studied.

Where it sits Chromosome 10, band 10q11.21 — between genes, 119.1 kb from LINC00841.

What each result means

A/A Two copies of the version the research linked to Coronary dominance (left or co-dominant vs right dominant). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Coronary dominance (left or co-dominant vs right dominant). That is a smaller link than two copies.
G/G No copy of the version the research linked to Coronary dominance (left or co-dominant vs right dominant). This is the starting point the study compared everyone against.
Source

Questions about rs2802490

What is rs2802490?

rs2802490 is a single position in the genome, in or near the near LINC00841 gene. Published research associates it with coronary dominance (left or co-dominant vs right dominant). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2802490 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2802490 come from?

GWAS Catalog, Cell 2025, PMID:40049164. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Coronary dominance (left or co-dominant vs right dominant) (rs2802490). MyGeneLog™. https://www.mygenelog.com/variants/rs2802490

← See all variants