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Who was studied 49,905 European ancestry cases, 752,392 European ancestry controls.
The effect
Each copy of the G allele shifted the measure 0.0522 higher (95% confidence interval 0.036-0.068); p = 1 × 10−10.
Where it sits Chromosome 6, band 6p25.3 — between genes, 5.1 kb from IRF4.
What each result means
A/ANo copy of the version the research linked to Basal cell carcinoma. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Basal cell carcinoma. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Basal cell carcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Communications biology · 2024 · PMID 38182794 · open access
Questions about rs2797304
What is rs2797304?
rs2797304 is a single position in the genome, in or near the near IRF4 gene. Published research associates it with basal cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2797304 linked to?
On MyGeneLog this position is linked to Basal Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs2797304 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2797304 come from?
GWAS Catalog, Communications biology 2024, PMID:38182794. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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