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Umbilical hernia

LYPLAL1-AS1 · rs2791544

Where this position leads

Condition: Umbilical Hernia

rs2791544 Condition: Umbilical Hernia Umbilical Hernia Condition rs2791544 rs2791544 LYPLAL1-AS1

What the study found

Who was studied 3,211 European ancestry cases, 272,335 European ancestry controls; replicated in 1,078 European ancestry cases, 90,770 European ancestry controls.

The effect The reported allele is A; the catalogue records no effect size ; p = 9 × 10−16.

How common The A allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 1, band 1q41 — in an intron of LYPLAL1-AS1.

What each result means

A/A Two copies of the version the research linked to Umbilical hernia. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Umbilical hernia. That is a smaller link than two copies.
G/G No copy of the version the research linked to Umbilical hernia. This is the starting point the study compared everyone against.
Source

Questions about rs2791544

What is rs2791544?

rs2791544 is a single position in the genome, in or near the LYPLAL1-AS1 gene. Published research associates it with umbilical hernia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2791544 linked to?

On MyGeneLog this position is linked to Umbilical Hernia. The research behind each link, and its sources, are set out on that condition page.

Does having rs2791544 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2791544 come from?

GWAS Catalog, Hernia : the journal of hernias and abdominal wall surgery 2022, PMID:34382107. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Umbilical hernia (rs2791544). MyGeneLog™. https://www.mygenelog.com/variants/rs2791544

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