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Systolic blood pressure (MTAG)

TMEM26-AS1 · rs2787724

Where this position leads

Condition: Blood Pressure

rs2787724 Condition: Blood Pressure Blood Pressure Condition rs2787724 rs2787724 TMEM26-AS1

What the study found

Who was studied at least 757,601 European ancestry individuals (MTAG boosted by 455,258 Alzheimer's disease samples).

The effect Each copy of the G allele shifted the measure 0.0115 higher (95% confidence interval 0.0081-0.015); p = 4 × 10−11.

Where it sits Chromosome 10, band 10q21.2 — in an intron of TMEM26-AS1.

What each result means

A/A No copy of the version the research linked to Systolic blood pressure (MTAG). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Systolic blood pressure (MTAG). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Systolic blood pressure (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2787724

What is rs2787724?

rs2787724 is a single position in the genome, in or near the TMEM26-AS1 gene. Published research associates it with systolic blood pressure (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2787724 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs2787724 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2787724 come from?

GWAS Catalog, Nature communications 2024, PMID:39537608. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Systolic blood pressure (MTAG) (rs2787724). MyGeneLog™. https://www.mygenelog.com/variants/rs2787724

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