Sensitive

Keratinocyte cancer (MTAG)

LINC00111 · rs2776348

Where this position leads

Condition: Keratinocyte Cancer

rs2776348 Condition: Keratinocyte Cancer Keratinocyte Cancer Condition rs2776348 rs2776348 LINC00111

What the study found

Who was studied at least 18,538 European ancestry cases, at least 340,302 European ancestry controls.

The effect Each copy of the A allele carried 1.09 times the odds of Keratinocyte cancer (MTAG) (95% confidence interval 1.06-1.1); p = 2 × 10−19.

How common The A allele had a frequency of about 66% in the people studied.

Where it sits Chromosome 21, band 21q22.3 — between genes, 12.4 kb from LINC00111.

What each result means

A/A Two copies of the version the research linked to Keratinocyte cancer (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Keratinocyte cancer (MTAG). That is a smaller link than two copies.
C/C No copy of the version the research linked to Keratinocyte cancer (MTAG). This is the starting point the study compared everyone against.
Source

Questions about rs2776348

What is rs2776348?

rs2776348 is a single position in the genome, in or near the LINC00111 gene. Published research associates it with keratinocyte cancer (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2776348 linked to?

On MyGeneLog this position is linked to Keratinocyte Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs2776348 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2776348 come from?

GWAS Catalog, Human molecular genetics 2019, PMID:31174203. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Keratinocyte cancer (MTAG) (rs2776348). MyGeneLog™. https://www.mygenelog.com/variants/rs2776348

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