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Lateral thalamic nuclei volume

DCDC1 · rs2774406

What the study found

Who was studied 30,114 white British ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0704 higher (95% confidence interval 0.054-0.087); p = 7 × 10−17.

How common The C allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 11, band 11p13 — in an intron of DCDC1.

What each result means

C/C Two copies of the version the research linked to Lateral thalamic nuclei volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Lateral thalamic nuclei volume. That is a smaller link than two copies.
T/T No copy of the version the research linked to Lateral thalamic nuclei volume. This is the starting point the study compared everyone against.
Source

Questions about rs2774406

What is rs2774406?

rs2774406 is a single position in the genome, in or near the DCDC1 gene. Published research associates it with lateral thalamic nuclei volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2774406 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2774406 come from?

GWAS Catalog, Nature communications 2021, PMID:34006833. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Lateral thalamic nuclei volume (rs2774406). MyGeneLog™. https://www.mygenelog.com/variants/rs2774406

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