Sensitive

Schizophrenia

LOC728586 · rs2764766

Where this position leads

Condition: Schizophrenia

rs2764766 Condition: Schizophrenia Schizophrenia Condition rs2764766 rs2764766 LOC728586

What the study found

Who was studied 14,023 East Asian ancestry cases, 33,640 European ancestry cases, 31,505 East Asian ancestry controls, 43,456 European ancestry controls.

The effect Each copy of the C allele carried 1.05 times the odds of Schizophrenia (95% confidence interval 1.04-1.07); p = 2 × 10−8.

Where it sits Chromosome 5, band 5q23.2 — in an intron of CCDC192.

What each result means

C/C Two copies of the version the research linked to Schizophrenia. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Schizophrenia. That is a smaller link than two copies.
G/G No copy of the version the research linked to Schizophrenia. This is the starting point the study compared everyone against.
Source

Questions about rs2764766

What is rs2764766?

rs2764766 is a single position in the genome, in or near the LOC728586 gene. Published research associates it with schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2764766 linked to?

On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.

Does having rs2764766 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2764766 come from?

GWAS Catalog, Schizophr Bull 2018, PMID:30285260. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Schizophrenia (rs2764766). MyGeneLog™. https://www.mygenelog.com/variants/rs2764766

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