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Hay fever and/or eczema

AHI1 · rs2746438

What the study found

Who was studied 84,034 European ancestry cases, 239,773 European ancestry controls.

The effect Each copy of the T allele carried 1.04 times the odds of Hay fever and/or eczema (95% confidence interval 1.028-1.051); p = 6 × 10−11.

How common The T allele had a frequency of about 44% in the people studied.

Where it sits Chromosome 6, band 6q23.3 — in an intron of AHI1.

What each result means

A/A No copy of the version the research linked to Hay fever and/or eczema. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Hay fever and/or eczema. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Hay fever and/or eczema. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs2746438

What is rs2746438?

rs2746438 is a single position in the genome, in or near the AHI1 gene. Published research associates it with hay fever and/or eczema. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2746438 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2746438 come from?

GWAS Catalog, Human molecular genetics 2019, PMID:31361310. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hay fever and/or eczema (rs2746438). MyGeneLog™. https://www.mygenelog.com/variants/rs2746438

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