Sensitive

Hirschsprung disease

RET · rs2742234

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Hirschsprung disease — no copies of the reported risk allele. (GWAS Catalog, Proc Natl Acad Sci U S A 2009, PMID:19196962)

C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hirschsprung disease. (GWAS Catalog, Proc Natl Acad Sci U S A 2009, PMID:19196962)

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hirschsprung disease compared to the general population. (GWAS Catalog, Proc Natl Acad Sci U S A 2009, PMID:19196962)

Source: GWAS Catalog, Proc Natl Acad Sci U S A 2009, PMID:19196962

Questions about rs2742234

What is rs2742234?

rs2742234 is a single position in the genome, in or near the RET gene. Published research associates it with hirschsprung disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs2742234 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2742234 come from?

GWAS Catalog, Proc Natl Acad Sci U S A 2009, PMID:19196962. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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