Standard
IgA nephropathy
DEFAs · rs2738048
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of IgA nephropathy compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with IgA nephropathy.
G/G
Published research associates this genotype with typical/baseline likelihood of IgA nephropathy — no copies of the reported risk allele.
Source
A genome-wide association study in Han Chinese identifies multiple susceptibility loci for IgA nephropathy
Yu XQ,
Li M,
Zhang H,
Low HQ,
Wei X,
Wang JQ,
Sun LD,
Sim KS,
Li Y,
Foo JN,
Wang W,
Li ZJ
and 13 more — show all
Yin XY,
Tang XQ,
Fan L,
Chen J,
Li RS,
Wan JX,
Liu ZS,
Lou TQ,
Zhu L,
Huang XJ,
Zhang XJ,
Liu ZH,
Liu JJ
Nature genetics · 2011 · PMID 22197929
Questions about rs2738048
What is rs2738048?
rs2738048 is a single position in the genome, in or near the DEFAs gene. Published research associates it with iga nephropathy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2738048 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2738048 come from?
GWAS Catalog, Nat Genet 2011, PMID:22197929. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants