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Hemoglobin concentration

DCDC1 · rs273613

What the study found

Who was studied 52,141 European ancestry females; replicated in 89,584 European ancestry females.

The effect Each copy of the T allele shifted the measure 0.0231 lower; p = 6 × 10−11.

How common The T allele had a frequency of about 33% in the people studied.

Where it sits Chromosome 11, band 11p14.1 — in an intron of DCDC1.

What each result means

C/C No copy of the version the research linked to Hemoglobin concentration. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Hemoglobin concentration. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Hemoglobin concentration. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs273613

What is rs273613?

rs273613 is a single position in the genome, in or near the DCDC1 gene. Published research associates it with hemoglobin concentration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs273613 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs273613 come from?

GWAS Catalog, The Journal of nutritional biochemistry 2023, PMID:35964923. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hemoglobin concentration (rs273613). MyGeneLog™. https://www.mygenelog.com/variants/rs273613

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