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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 303 European ancestry individuals.
The effect
The reported allele is T; the catalogue records no effect size
; p = 3 × 10−26.
How common The T allele had a frequency of about 42% in the people studied.
Where it sits Chromosome 6, band 6p22.1 — in the 3′ untranslated region of HLA-A.
What each result means
G/GNo copy of the version the research linked to interferon-related traits. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to interferon-related traits. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to interferon-related traits. That is the strongest link of the three results. A link in a study is not a diagnosis.
PLoS genetics · 2020 · PMID 33104735 · open access
Questions about rs2735099
What is rs2735099?
rs2735099 is a single position in the genome, in or near the HLA-A gene. Published research associates it with interferon-related traits. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2735099 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2735099 come from?
GWAS Catalog, PLoS genetics 2020, PMID:33104735. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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