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The effect
Each copy of the T allele shifted the measure 0.036 lower (95% confidence interval 0.027-0.045); p = 8 × 10−16.
Where it sits Chromosome 6, band 6p21.33 — between genes, 0.3 kb from RPL15P4.
What each result means
A/ANo copy of the version the research linked to Hip circumference adjusted for BMI. This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Hip circumference adjusted for BMI. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Hip circumference adjusted for BMI. That is the strongest link of the three results. A link in a study is not a diagnosis.
Scientific reports · 2021 · PMID 34021172 · open access
Questions about rs2734580
What is rs2734580?
rs2734580 is a single position in the genome, in or near the RPL15P4 gene. Published research associates it with hip circumference adjusted for bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs2734580 linked to?
On MyGeneLog this position is linked to Hip Circumference. The research behind each link, and its sources, are set out on that condition page.
Does having rs2734580 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2734580 come from?
GWAS Catalog, Scientific reports 2021, PMID:34021172. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 523Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total5Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Hip circumference adjusted for BMI (rs2734580). MyGeneLog™. https://www.mygenelog.com/variants/rs2734580