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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 4,897 European ancestry individuals; replicated in 1,979 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.178 ng/mL lower (95% confidence interval 0.14-0.21); p = 4 × 10−25.
How common The C allele had a frequency of about 75% in the people studied.
Where it sits Chromosome 5, band 5q35.3 — inside F12.
What each result means
C/CTwo copies of the version the research linked to Osteopontin levels in chronic kidney disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Osteopontin levels in chronic kidney disease. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Osteopontin levels in chronic kidney disease. This is the starting point the study compared everyone against.
PLoS genetics · 2022 · PMID 35385482 · open access
Questions about rs2731673
What is rs2731673?
rs2731673 is a single position in the genome, in or near the GRK6 gene. Published research associates it with osteopontin levels in chronic kidney disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs2731673 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs2731673 come from?
GWAS Catalog, PLoS genetics 2022, PMID:35385482. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Osteopontin levels in chronic kidney disease (rs2731673). MyGeneLog™. https://www.mygenelog.com/variants/rs2731673