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Body mass index

PDZRN4-AS1 · rs2730829

Where this position leads

Conditions: Obesity and Body Weight, Childhood Body Mass Index

rs2730829 Condition: Obesity and Body Weight Obesity and Body Weight Condition Condition: Childhood Body Mass Index Childhood Body Mass Index Condition rs2730829 rs2730829 PDZRN4-AS1

What the study found

Who was studied 1,122,049 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0165 lower (95% confidence interval 0.014-0.019); p = 1 × 10−34.

Where it sits Chromosome 12, band 12q12 — in an intron of PDZRN4-AS1.

What each result means

C/C Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
T/T No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
Source

Questions about rs2730829

What is rs2730829?

rs2730829 is a single position in the genome, in or near the PDZRN4-AS1 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs2730829 linked to?

On MyGeneLog this position is linked to Obesity and Body Weight, Childhood Body Mass Index. The research behind each link, and its sources, are set out on that condition page.

Does having rs2730829 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs2730829 come from?

GWAS Catalog, Nature communications 2022, PMID:36581621. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs2730829). MyGeneLog™. https://www.mygenelog.com/variants/rs2730829

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